Neuron-targeted caveolin-1 improves neuromuscular function and extends survival in SOD1(G93A) mice

Interventions that preserve motor neurons or restore functional motor neuroplasticity may extend longevity in amyotrophic lateral sclerosis (ALS). Delivery of neurotrophins may potentially revive degenerating motor neurons, yet this approach is dependent on the proper subcellular localization of neu...

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Dades bibliogràfiques
Publicat a:FASEB J
Autors principals: Sawada, Atsushi, Wang, Shanshan, Jian, Minyu, Leem, Joseph, Wackerbarth, Jesse, Egawa, Junji, Schilling, Jan M., Platoshyn, Oleksandr, Zemljic-Harpf, Alice, Roth, David M., Patel, Hemal H., Patel, Piyush M., Marsala, Martin, Head, Brian P.
Format: Artigo
Idioma:Inglês
Publicat: Federation of American Societies for Experimental Biology 2019
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529340/
https://ncbi.nlm.nih.gov/pubmed/30894019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201802652RR
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