Neuron-targeted caveolin-1 improves neuromuscular function and extends survival in SOD1(G93A) mice

Interventions that preserve motor neurons or restore functional motor neuroplasticity may extend longevity in amyotrophic lateral sclerosis (ALS). Delivery of neurotrophins may potentially revive degenerating motor neurons, yet this approach is dependent on the proper subcellular localization of neu...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Sawada, Atsushi, Wang, Shanshan, Jian, Minyu, Leem, Joseph, Wackerbarth, Jesse, Egawa, Junji, Schilling, Jan M., Platoshyn, Oleksandr, Zemljic-Harpf, Alice, Roth, David M., Patel, Hemal H., Patel, Piyush M., Marsala, Martin, Head, Brian P.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529340/
https://ncbi.nlm.nih.gov/pubmed/30894019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201802652RR
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