Loss‐of‐function of miR‐142 by hypermethylation promotes TGF‐β‐mediated tumour growth and metastasis in hepatocellular carcinoma

OBJECTIVES: Hypermethylation‐induced epigenetic silencing of tumour suppressor genes (TSGs) are frequent events during carcinogenesis. MicroRNA‐142 (miR‐142) is found to be dysregulated in cancer patients to participate into tumour growth, metastasis and angiogenesis. However, the tumour suppressive...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Prolif
Egile Nagusiak: Yu, Qiangfeng, Xiang, Leyang, Yin, Libo, Liu, Xincheng, Yang, Dinghua, Zhou, Jianyin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2017
Gaiak:
Original Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529086/
https://ncbi.nlm.nih.gov/pubmed/28963738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12384
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