Loss‐of‐function of miR‐142 by hypermethylation promotes TGF‐β‐mediated tumour growth and metastasis in hepatocellular carcinoma

OBJECTIVES: Hypermethylation‐induced epigenetic silencing of tumour suppressor genes (TSGs) are frequent events during carcinogenesis. MicroRNA‐142 (miR‐142) is found to be dysregulated in cancer patients to participate into tumour growth, metastasis and angiogenesis. However, the tumour suppressive...

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Vydáno v:Cell Prolif
Hlavní autoři: Yu, Qiangfeng, Xiang, Leyang, Yin, Libo, Liu, Xincheng, Yang, Dinghua, Zhou, Jianyin
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529086/
https://ncbi.nlm.nih.gov/pubmed/28963738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12384
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