Loss‐of‐function of miR‐142 by hypermethylation promotes TGF‐β‐mediated tumour growth and metastasis in hepatocellular carcinoma

OBJECTIVES: Hypermethylation‐induced epigenetic silencing of tumour suppressor genes (TSGs) are frequent events during carcinogenesis. MicroRNA‐142 (miR‐142) is found to be dysregulated in cancer patients to participate into tumour growth, metastasis and angiogenesis. However, the tumour suppressive...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Cell Prolif
Autores principales: Yu, Qiangfeng, Xiang, Leyang, Yin, Libo, Liu, Xincheng, Yang, Dinghua, Zhou, Jianyin
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529086/
https://ncbi.nlm.nih.gov/pubmed/28963738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12384
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares