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Apoptosis induction in K562 human myelogenous leukaemia cells is connected to the modulation of Wnt/β‐catenin signalling by BHX, a novel pyrazoline derivative

OBJECTIVES: The goal of this study was to explore the effects of BHX on human chronic myeloid leukaemia (CML) cells and to elucidate the underlying molecular mechanism. MATERIALS AND METHODS: CML cell line K562 cells were treated with BHX. The effects of BHX on cell proliferation, apoptosis and cell...

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Опубликовано в: :Cell Prolif
Главные авторы: Bao, Hanmei, Zhang, Qing, Du, Yibo, Zhang, Cai, Xu, Hui, Zhu, Zhongling, Yan, Zhao
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6528944/
https://ncbi.nlm.nih.gov/pubmed/29341317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12433
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