BHX Inhibits the Wnt Signaling Pathway by Suppressing β-catenin Transcription in the Nucleus

BHX (N-(4-hydroxybenzyl)-1,3,4-triphenyl-4,5-dihydro-1H-pyrazole-5-carboxamide), a Wnt signaling pathway inhibitor, effectively inhibits tumor cell growth, but the underlying mechanism is unclear. Thus, we aim to investigate the effects and associated mechanism of BHX action on A549 and MCF-7 cell l...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Ding, Fengxia, Wang, Meisa, Du, Yibo, Du, Shuangshuang, Zhu, Zhongling, Yan, Zhao
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133598/
https://ncbi.nlm.nih.gov/pubmed/27910912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38331
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