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CD44 targets Wnt/β-catenin pathway to mediate the proliferation of K562 cells

BACKGROUND: Chronic myeloid leukemia is a clonal myeloproliferative disorder disease in which BCR/ABL plays an important role as an oncoprotein and molecular target. Despite the success of targeted therapy using tyrosine kinase inhibitors, CML remains largely incurable, most likely due to the treatm...

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Bibliographic Details
Main Authors: Chang, Guoqiang, Zhang, Hongju, Wang, Jian, Zhang, Yujuan, Xu, Hua, Wang, Chijuan, Zhang, Hairui, Ma, Li, Li, Qinghua, Pang, Tianxiang
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176735/
https://ncbi.nlm.nih.gov/pubmed/24257075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-13-117
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