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CD44 targets Wnt/β-catenin pathway to mediate the proliferation of K562 cells

BACKGROUND: Chronic myeloid leukemia is a clonal myeloproliferative disorder disease in which BCR/ABL plays an important role as an oncoprotein and molecular target. Despite the success of targeted therapy using tyrosine kinase inhibitors, CML remains largely incurable, most likely due to the treatm...

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Detalhes bibliográficos
Main Authors: Chang, Guoqiang, Zhang, Hongju, Wang, Jian, Zhang, Yujuan, Xu, Hua, Wang, Chijuan, Zhang, Hairui, Ma, Li, Li, Qinghua, Pang, Tianxiang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176735/
https://ncbi.nlm.nih.gov/pubmed/24257075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-13-117
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