Triptolide Induces Glioma Cell Autophagy and Apoptosis via Upregulating the ROS/JNK and Downregulating the Akt/mTOR Signaling Pathways

Apoptosis and autophagy are the two prominent forms of developmental cell death, and researches have shown that crosstalk exists between these two processes. A prior study demonstrated that triptolide inhibited the proliferation of malignant glioma cells. However, whether apoptosis and autophagy par...

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Bibliographische Detailangaben
Veröffentlicht in:Front Oncol
Hauptverfasser: Liu, Xihong, Zhao, Peiyuan, Wang, Xiujuan, Wang, Lei, Zhu, Yingjun, Gao, Wei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Oncology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6528693/
https://ncbi.nlm.nih.gov/pubmed/31157167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00387
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