p53 mutation regulates PKD genes and results in co-occurrence of PKD and tumorigenesis

OBJECTIVE: Polycystic kidney disease (PKD) is the major cause of kidney failure and mortality in humans. It has always been suspected that the development of cystic kidney disease shares features with tumorigenesis, although the evidence is unclear. METHODS: We crossed p53 mutant mice (p53N236S, p53...

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Detalhes bibliográficos
Publicado no:Cancer Biol Med
Main Authors: Li, Haili, Zhang, Yongjin, Dan, Juhua, Zhou, Ruoyu, Li, Cui, Li, Rong, Wu, Xiaoming, Kumar Singh, Sanjay, T. Chang, Jeffrey, Yang, Julun, Luo, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: Chinese Anti-Cancer Association 2019
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6528458/
https://ncbi.nlm.nih.gov/pubmed/31119048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.20892/j.issn.2095-3941.2018.0170
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