p53 mutation regulates PKD genes and results in co-occurrence of PKD and tumorigenesis

OBJECTIVE: Polycystic kidney disease (PKD) is the major cause of kidney failure and mortality in humans. It has always been suspected that the development of cystic kidney disease shares features with tumorigenesis, although the evidence is unclear. METHODS: We crossed p53 mutant mice (p53N236S, p53...

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Bibliografiset tiedot
Julkaisussa:Cancer Biol Med
Päätekijät: Li, Haili, Zhang, Yongjin, Dan, Juhua, Zhou, Ruoyu, Li, Cui, Li, Rong, Wu, Xiaoming, Kumar Singh, Sanjay, T. Chang, Jeffrey, Yang, Julun, Luo, Ying
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Chinese Anti-Cancer Association 2019
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Original Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6528458/
https://ncbi.nlm.nih.gov/pubmed/31119048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.20892/j.issn.2095-3941.2018.0170
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