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Impact of cancer mutational signatures on transcription factor motifs in the human genome
BACKGROUND: Somatic mutations in cancer genomes occur through a variety of molecular mechanisms, which contribute to different mutational patterns. To summarize these, mutational signatures have been defined using a large number of cancer genomes, and related to distinct mutagenic processes. Each ca...
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| Publicado no: | BMC Med Genomics |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6528224/ https://ncbi.nlm.nih.gov/pubmed/31109337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-019-0525-4 |
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