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Impact of cancer mutational signatures on transcription factor motifs in the human genome

BACKGROUND: Somatic mutations in cancer genomes occur through a variety of molecular mechanisms, which contribute to different mutational patterns. To summarize these, mutational signatures have been defined using a large number of cancer genomes, and related to distinct mutagenic processes. Each ca...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:BMC Med Genomics
Prif Awduron: Yiu Chan, Calvin Wing, Gu, Zuguang, Bieg, Matthias, Eils, Roland, Herrmann, Carl
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6528224/
https://ncbi.nlm.nih.gov/pubmed/31109337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-019-0525-4
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