Impaired circulating myeloid CD1c+ dendritic cell function in human glioblastoma is restored by p38 inhibition – implications for the next generation of DC vaccines

Current treatments for glioblastoma (GBM) have limited efficacy and significant morbidity and therefore new strategies are urgently needed. Dendritic cells have the power to create anti-tumor immune responses. The greater potency of circulating dendritic cells (DC) over laboratory-generated monocyte...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Adhikaree, Jason, Franks, Hester Ann, Televantos, Constantinos, Vaghela, Poonam, Kaur, Aanchal Preet, Walker, David, Schmitz, Marc, Jackson, Andrew Mark, Patel, Poulam Manubhai
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6527277/
https://ncbi.nlm.nih.gov/pubmed/31143512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2019.1593803
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