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TLR4 (toll-like receptor 4) activation suppresses autophagy through inhibition of FOXO3 and impairs phagocytic capacity of microglia

Macroautophagy/autophagy is a lysosome-dependent catabolic process for the turnover of proteins and organelles in eukaryotes. Autophagy plays an important role in immunity and inflammation, as well as metabolism and cell survival. Diverse immune and inflammatory signals induce autophagy in macrophag...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Lee, Ji-Won, Nam, Hyeri, Kim, Leah Eunjung, Jeon, Yoonjeong, Min, Hyunjung, Ha, Shinwon, Lee, Younghwan, Kim, Seon-Young, Lee, Sung Joong, Kim, Eun-Kyoung, Yu, Seong-Woon
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6526818/
https://ncbi.nlm.nih.gov/pubmed/30523761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1556946
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