TLR4 (toll-like receptor 4) activation suppresses autophagy through inhibition of FOXO3 and impairs phagocytic capacity of microglia

Macroautophagy/autophagy is a lysosome-dependent catabolic process for the turnover of proteins and organelles in eukaryotes. Autophagy plays an important role in immunity and inflammation, as well as metabolism and cell survival. Diverse immune and inflammatory signals induce autophagy in macrophag...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Autophagy
Autori principali: Lee, Ji-Won, Nam, Hyeri, Kim, Leah Eunjung, Jeon, Yoonjeong, Min, Hyunjung, Ha, Shinwon, Lee, Younghwan, Kim, Seon-Young, Lee, Sung Joong, Kim, Eun-Kyoung, Yu, Seong-Woon
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2018
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6526818/
https://ncbi.nlm.nih.gov/pubmed/30523761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1556946
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi