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TLR4 (toll-like receptor 4) activation suppresses autophagy through inhibition of FOXO3 and impairs phagocytic capacity of microglia

Macroautophagy/autophagy is a lysosome-dependent catabolic process for the turnover of proteins and organelles in eukaryotes. Autophagy plays an important role in immunity and inflammation, as well as metabolism and cell survival. Diverse immune and inflammatory signals induce autophagy in macrophag...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Autophagy
Egile Nagusiak: Lee, Ji-Won, Nam, Hyeri, Kim, Leah Eunjung, Jeon, Yoonjeong, Min, Hyunjung, Ha, Shinwon, Lee, Younghwan, Kim, Seon-Young, Lee, Sung Joong, Kim, Eun-Kyoung, Yu, Seong-Woon
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6526818/
https://ncbi.nlm.nih.gov/pubmed/30523761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1556946
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