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DIABLO/SMAC mimetics selectively kill HIV-1-infected resting memory CD4(+) T cells: a potential role in a cure strategy for HIV-1 infection

Despite advances in HIV therapy, there is no cure, and lifelong antiretroviral treatment is required to suppress viral replication. We hypothesized that HIV maintains the survival of latently infected CD4(+) T cells through increased expression of cell survival factors including XIAP, BIRC2 and BECN...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Campbell, Grant R., Spector, Stephen A.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6526817/
https://ncbi.nlm.nih.gov/pubmed/30653393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1569950
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