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RUBCNL/Pacer and RUBCN/Rubicon in regulation of autolysosome formation and lipid metabolism
Recently, we identified a vertebrate-specific macroautophagy/autophagy regulator, RUBCNL/Pacer, which promotes autolysosome formation by engaging the class III phosphatidylinositol 3-kinase (PtdIns3K) and HOPS complexes. Hepatocyte-specific rubcnl knockout in mice results in impaired autophagy flux,...
Tallennettuna:
| Julkaisussa: | Autophagy |
|---|---|
| Päätekijät: | , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Taylor & Francis
2019
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6526810/ https://ncbi.nlm.nih.gov/pubmed/30894088 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1596500 |
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