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Rubicon controls endosome maturation as a Rab7 effector

The activation and recruitment of the small GTPase Rab7 to early endosome is a critical step for early to late endosome maturation, a process that requires the class III phosphatidylinositol 3-kinase (PI3KC3) and GTPase regulators. However, the molecular mechanism underlying Rab7 activation and endo...

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Detalhes bibliográficos
Main Authors: Sun, Qiming, Westphal, Wiebke, Wong, Kwun Ngok, Tan, Irena, Zhong, Qing
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2984168/
https://ncbi.nlm.nih.gov/pubmed/20974968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1010554107
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