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Isolation, Structure, and Total Synthesis of the Marine Macrolide Mangrolide D

The isolation, characterization and total synthesis of the macrocyclic polyene mangrolide D is reported. A 16-step total synthesis relies on robust Suzuki and ring-closing metathesis reactions, and an iron-catalyzed hydroazidation of an exo-methylene substituted tetrahydropyran as a key step for the...

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Bibliografski detalji
Izdano u:Org Lett
Glavni autori: Gong, Junyu, Li, Wei, Fu, Peng, MacMillan, John, De Brabander, Jef K.
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6526702/
https://ncbi.nlm.nih.gov/pubmed/30957503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.9b01126
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