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Isolation, Structure, and Total Synthesis of the Marine Macrolide Mangrolide D
The isolation, characterization and total synthesis of the macrocyclic polyene mangrolide D is reported. A 16-step total synthesis relies on robust Suzuki and ring-closing metathesis reactions, and an iron-catalyzed hydroazidation of an exo-methylene substituted tetrahydropyran as a key step for the...
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| Publicado no: | Org Lett |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6526702/ https://ncbi.nlm.nih.gov/pubmed/30957503 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.9b01126 |
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