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Structure elucidation of nigricanoside A through enantioselective total synthesis

Nigricanoside A was isolated from green alga, and its dimethyl ester was found to display potent cytotoxicity. Its scarcity prevented a full structure elucidation, leaving total synthesis as the only means to determine its relative and absolute stereochemistry and to explore its biological activity....

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Chen, Jie, Koswatta, Panduka, DeBergh, J. Robb, Fu, Peng, Pan, Ende, MacMillan, John B., Ready, Joseph M.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751885/
https://ncbi.nlm.nih.gov/pubmed/26877863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc00281h
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