Loss of the transcriptional repressor TGIF1 results in enhanced Kras-driven development of pancreatic cancer

BACKGROUND: The TG-interacting factor 1 (TGIF1) gene, which encodes a nuclear transcriptional corepressor of the TGFβ1/Smad signaling pathway, has been implicated in the pathogenesis of various types of human cancer; however, its role in pancreatic ductal adenocarcinoma (PDAC) has yet to be elucidat...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cancer
Prif Awduron: Weng, Ching-Chieh, Hsieh, Mei-Jen, Wu, Chia-Chen, Lin, Yu-Chun, Shan, Yan-Shen, Hung, Wen-Chun, Chen, Li-Tzong, Cheng, Kuang-Hung
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2019
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6526617/
https://ncbi.nlm.nih.gov/pubmed/31109321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-019-1023-1
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