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Loss of the transcriptional repressor TGIF1 results in enhanced Kras-driven development of pancreatic cancer
BACKGROUND: The TG-interacting factor 1 (TGIF1) gene, which encodes a nuclear transcriptional corepressor of the TGFβ1/Smad signaling pathway, has been implicated in the pathogenesis of various types of human cancer; however, its role in pancreatic ductal adenocarcinoma (PDAC) has yet to be elucidat...
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| Publicado no: | Mol Cancer |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6526617/ https://ncbi.nlm.nih.gov/pubmed/31109321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-019-1023-1 |
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