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Loss of PGC-1α in RPE induces mesenchymal transition and promotes retinal degeneration
The retinal pigment epithelium (RPE) supports visual processing and photoreceptor homeostasis via energetically demanding cellular functions. Here, we describe the consequences of repressing peroxisome proliferator-activated receptor γ coactivator-1 α (PGC-1α), a master regulator of mitochondrial fu...
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| Publicado no: | Life Sci Alliance |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Life Science Alliance LLC
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6526284/ https://ncbi.nlm.nih.gov/pubmed/31101737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201800212 |
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