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Loss of PGC-1α in RPE induces mesenchymal transition and promotes retinal degeneration
The retinal pigment epithelium (RPE) supports visual processing and photoreceptor homeostasis via energetically demanding cellular functions. Here, we describe the consequences of repressing peroxisome proliferator-activated receptor γ coactivator-1 α (PGC-1α), a master regulator of mitochondrial fu...
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| Pubblicato in: | Life Sci Alliance |
|---|---|
| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Life Science Alliance LLC
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6526284/ https://ncbi.nlm.nih.gov/pubmed/31101737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201800212 |
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