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Eltrombopag Promotes DNA Repair in Human Hematopoietic Stem and Progenitor Cells
A causal link between hematopoietic stem/progenitor cell (HSPC) dysfunction and DNA damage accrual has been proposed. Clinically relevant strategies to maintain genome integrity in these cells are needed. Here we report that eltrombopag, a small molecule agonist of the thrombopoietin (TPO) receptor...
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| Publicado no: | Exp Hematol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6526067/ https://ncbi.nlm.nih.gov/pubmed/30986494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2019.03.002 |
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