Lysostaphin and BMP-2 co-delivery reduces S. aureus infection and regenerates critical-sized segmental bone defects

Staphylococcus aureus is the most common pathogen associated with bacterial infections in orthopedic procedures. Infections often lead to implant failure and subsequent removal, motivating the development of bifunctional materials that both promote repair and prevent failure due to infection. Lysost...

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Publicat a:Sci Adv
Autors principals: Johnson, Christopher T., Sok, Mary Caitlin P., Martin, Karen E., Kalelkar, Pranav P., Caplin, Jeremy D., Botchwey, Edward A., García, Andrés J.
Format: Artigo
Idioma:Inglês
Publicat: American Association for the Advancement of Science 2019
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6524983/
https://ncbi.nlm.nih.gov/pubmed/31114804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaw1228
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