Microparticles for Sustained Growth Factor Delivery in the Regeneration of Critically-Sized Segmental Tibial Bone Defects

This study trialled the controlled delivery of growth factors within a biodegradable scaffold in a large segmental bone defect model. We hypothesised that co-delivery of vascular endothelial growth factor (VEGF) and platelet derived growth factor (PDGF) followed by bone morphogenetic protein-2 (BMP-...

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Detalhes bibliográficos
Publicado no:Materials (Basel)
Main Authors: Kirby, Giles T. S., White, Lisa J., Steck, Roland, Berner, Arne, Bogoevski, Kristofor, Qutachi, Omar, Jones, Brendan, Saifzadeh, Siamak, Hutmacher, Dietmar W., Shakesheff, Kevin M., Woodruff, Maria A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5502923/
https://ncbi.nlm.nih.gov/pubmed/28773384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ma9040259
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