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Delivery of S1P Receptor-Targeted Drugs via Biodegradable Polymer Scaffolds Enhances Bone Regeneration in a Critical Size Cranial Defect()

Biodegradable polymer scaffolds can be used to deliver soluble factors to enhance osseous remodeling in bone defects. To this end, we designed a poly(lactic-co-glycolic acid) (PLAGA) microsphere scaffold to sustain the release of FTY720, a selective agonist for sphingosine 1-phosphate (S1P) receptor...

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Hlavní autoři: Das, Anusuya, Tanner, Shaun, Barker, Daniel A., Green, David, Botchwey, Edward A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3951302/
https://ncbi.nlm.nih.gov/pubmed/23640833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm.a.34779
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