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Bethesda Assay for Detecting Inhibitory Anti-ADAMTS13 Antibodies in Immune-Mediated Thrombotic Thrombocytopenic Purpura

A diagnosis of thrombotic thrombocytopenic purpura (TTP) is confirmed by a severe deficiency (<10%) of a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13 (ADAMTS13) activity. Autoantibodies to ADAMTS13 can be detected with a simplified enzyme-linked immunosorbent as...

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Bibliographic Details
Published in:TH Open
Main Authors: Vendramin, Chiara, Thomas, Mari, Westwood, John-Paul, Scully, Marie
Format: Artigo
Language:Inglês
Published: Georg Thieme Verlag KG 2018
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6524890/
https://ncbi.nlm.nih.gov/pubmed/31249957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0038-1672187
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