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Dependence of the Formation of Tau and Aβ Peptide Mixed Aggregates on the Secondary Structure of the N-terminal Region of Aβ

One of the hallmarks of Alzheimer’s disease is the formation of aggregates of the tau protein, a process that can be facilitated by the presence of fibrils formed by the Amyloid β peptide (Aβ). However, the mechanism that triggers tau aggregation is still a matter of debate. The effect of Aβ(40) fib...

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Veröffentlicht in:J Phys Chem B
Hauptverfasser: Rojas, Ana V., Maisuradze, Gia G., Scheraga, Harold A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6524542/
https://ncbi.nlm.nih.gov/pubmed/29940109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.8b04647
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