Harnessing Androgen Receptor Pathway Activation for Targeted Alpha Particle Radioimmunotherapy of Breast Cancer

PURPOSE: The impact of androgen receptor (AR) activity in breast cancer biology is unclear. We characterized and tested a novel therapy to an AR-governed target in breast cancer. EXPERIMENTAL DESIGN: We evaluated the expression of prototypical AR gene products human kallikrein 2 (hK2) and PSA in bre...

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Detaylı Bibliyografya
Yayımlandı:Clin Cancer Res
Asıl Yazarlar: Thorek, Daniel L.J., Ku, Anson T., Mitsiades, Nicholas, Veach, Darren, Watson, Philip A., Metha, Dipti, Strand, Sven-Erik, Sharma, Sai Kiran, Lewis, Jason S., Abou, Diane S., Lilja, Hans G., Larson, Steven M., McDevitt, Michael R., Ulmert, David
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6524527/
https://ncbi.nlm.nih.gov/pubmed/30254080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-1521
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