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5-Arylidene(chromenyl-methylene)-thiazolidinediones: Potential New Agents against Mutant Oncoproteins K-Ras, N-Ras and B-Raf in Colorectal Cancer and Melanoma

Background and objectives: Cancer represents the miscommunication between and within the body cells. The mutations of the oncogenes encoding the MAPK pathways play an important role in the development of tumoral diseases. The mutations of KRAS and BRAF oncogenes are involved in colorectal cancer and...

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Detalhes bibliográficos
Publicado no:Medicina (Kaunas)
Main Authors: Nastasă, Cristina, Tamaian, Radu, Oniga, Ovidiu, Tiperciuc, Brîndușa
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6524019/
https://ncbi.nlm.nih.gov/pubmed/30935124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/medicina55040085
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