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Study of the Relationships between the Structure, Lipophilicity and Biological Activity of Some Thiazolyl-carbonyl-thiosemicarbazides and Thiazolyl-azoles

Lipophilicity, as one of the most important physicochemical parameters of bioactive molecules, was investigated for twenty-two thiazolyl-carbonyl-thiosemicarbazides and thiazolyl-azoles. The determination was carried out by reversed-phase thin-layer chromatography, using a binary isopropanol-water m...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Tamaian, Radu, Moţ, Augustin, Silaghi-Dumitrescu, Radu, Ionuţ, Ioana, Stana, Anca, Oniga, Ovidiu, Nastasă, Cristina, Benedec, Daniela, Tiperciuc, Brînduşa
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6332165/
https://ncbi.nlm.nih.gov/pubmed/26690402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules201219841
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