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Mining for Oxysterols in Cyp7b1(−/−) Mouse Brain and Plasma: Relevance to Spastic Paraplegia Type 5
Deficiency in cytochrome P450 (CYP) 7B1, also known as oxysterol 7α-hydroxylase, in humans leads to hereditary spastic paraplegia type 5 (SPG5) and in some cases in infants to liver disease. SPG5 is medically characterized by loss of motor neurons in the corticospinal tract. In an effort to gain a b...
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| 出版年: | Biomolecules |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
MDPI
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6523844/ https://ncbi.nlm.nih.gov/pubmed/31013940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9040149 |
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