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The Modulation of Chitosan-DNA Interaction by Concentration and pH in Solution

Chitosan has been widely used to prepare a DNA carrier for highly efficient and non-toxic gene therapy. In the present study, we investigated DNA charge neutralization and compaction by chitosan in solutions of various pH levels by dynamic light scattering (DLS), magnetic tweezers (MT), and atomic f...

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書誌詳細
出版年:Polymers (Basel)
主要な著者: Ma, Fangqin, Wang, Yanwei, Yang, Guangcan
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6523332/
https://ncbi.nlm.nih.gov/pubmed/30970619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/polym11040646
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