Evaluation of the published kinase inhibitor set to identify multiple inhibitors of bacterial ATP-dependent mur ligases

The Mur ligases form a series of consecutive enzymes that participate in the intracellular steps of bacterial peptidoglycan biosynthesis. They therefore represent interesting targets for antibacterial drug discovery. MurC, D, E and F are all ATP-dependent ligases. Accordingly, with the aim being to...

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發表在:J Enzyme Inhib Med Chem
Main Authors: Hrast, Martina, Rožman, Kaja, Ogris, Iza, Škedelj, Veronika, Patin, Delphine, Sova, Matej, Barreteau, Hélène, Gobec, Stanislav, Grdadolnik, Simona Golič, Zega, Anamarija
格式: Artigo
語言:Inglês
出版: Taylor & Francis 2019
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6522912/
https://ncbi.nlm.nih.gov/pubmed/31072165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2019.1608981
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