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The formation of all-cis-(multi)fluorinated piperidines by a dearomatization-hydrogenation process

Piperidines and fluorine-substituents are both independently indispensable components in pharmaceuticals, agrochemicals and materials. Logically, the incorporation of fluorine atoms into piperidine scaffolds is therefore an area of tremendous potential. However, synthetic approaches towards the form...

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Pubblicato in:Nat Chem
Autori principali: Nairoukh, Zackaria, Wollenburg, Marco, Schlepphorst, Christoph, Bergander, Klaus, Glorius, Frank
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6522351/
https://ncbi.nlm.nih.gov/pubmed/30664720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41557-018-0197-2
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