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The formation of all-cis-(multi)fluorinated piperidines by a dearomatization-hydrogenation process
Piperidines and fluorine-substituents are both independently indispensable components in pharmaceuticals, agrochemicals and materials. Logically, the incorporation of fluorine atoms into piperidine scaffolds is therefore an area of tremendous potential. However, synthetic approaches towards the form...
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| Veröffentlicht in: | Nat Chem |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6522351/ https://ncbi.nlm.nih.gov/pubmed/30664720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41557-018-0197-2 |
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