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The formation of all-cis-(multi)fluorinated piperidines by a dearomatization-hydrogenation process

Piperidines and fluorine-substituents are both independently indispensable components in pharmaceuticals, agrochemicals and materials. Logically, the incorporation of fluorine atoms into piperidine scaffolds is therefore an area of tremendous potential. However, synthetic approaches towards the form...

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Publicado en:Nat Chem
Main Authors: Nairoukh, Zackaria, Wollenburg, Marco, Schlepphorst, Christoph, Bergander, Klaus, Glorius, Frank
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6522351/
https://ncbi.nlm.nih.gov/pubmed/30664720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41557-018-0197-2
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