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Glutathione S-Transferases as Regulators of Kinase Pathways and Anticancer Drug Targets
Anticancer drug development using the platform of glutathione (GSH), glutathione S-transferases (GST) and pathways that maintain thiol homeostasis has recently produced a number of lead compounds. GSTπ is a prevalent protein in many solid tumors and is overexpressed in cancers resistant to drugs. It...
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| Veröffentlicht in: | Methods Enzymol |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6522258/ https://ncbi.nlm.nih.gov/pubmed/16399394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0076-6879(05)01019-0 |
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