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Glutathione S-Transferases as Regulators of Kinase Pathways and Anticancer Drug Targets

Anticancer drug development using the platform of glutathione (GSH), glutathione S-transferases (GST) and pathways that maintain thiol homeostasis has recently produced a number of lead compounds. GSTπ is a prevalent protein in many solid tumors and is overexpressed in cancers resistant to drugs. It...

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Detalhes bibliográficos
Publicado no:Methods Enzymol
Main Authors: Townsend, Danyelle M., Findlay, Victoria L., Tew, Kenneth D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6522258/
https://ncbi.nlm.nih.gov/pubmed/16399394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0076-6879(05)01019-0
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