MIIP inhibits the growth of prostate cancer via interaction with PP1α and negative modulation of AKT signaling

BACKGROUND: Over-activation of phosphatidylinositol 3-kinase (PI3K)-AKT-mammalian target of rapamycin (mTOR) signaling pathway is one of important mechanisms to promote castration resistant prostate cancer, the final stage of prostate cancer (PCa). Dysregulation of PP1-meditaed AKT dephosphorylation...

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Detalhes bibliográficos
Publicado no:Cell Commun Signal
Main Authors: Yan, Guang, Ru, Yi, Yan, Fengqi, Xiong, Xin, Hu, Wei, Pan, Tao, Sun, Jianming, Zhang, Chi, Wang, Qinghao, Li, Xia
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6521544/
https://ncbi.nlm.nih.gov/pubmed/31092266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-019-0355-1
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