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Time-dependent antagonist-agonist switching in receptor tyrosine kinase-mediated signaling
BACKGROUND: ErbB4/HER4 is a unique member of the ErbB family of receptor tyrosine kinases concerning its activation of anti-proliferative JAK2-STAT5 pathway when stimulated by ligand Neuregulin (NRG). Activation of this pathway leads to expression of genes like β-casein which promote cell differenti...
Tallennettuna:
| Julkaisussa: | BMC Bioinformatics |
|---|---|
| Päätekijät: | , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
BioMed Central
2019
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6521356/ https://ncbi.nlm.nih.gov/pubmed/31092187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-2816-3 |
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