All-Trans-Retinoic Acid Suppresses Neointimal Hyperplasia and Inhibits Vascular Smooth Muscle Cell Proliferation and Migration via Activation of AMPK Signaling Pathway

The proliferation and migration of vascular smooth muscle cells (VSMC) is extensively involved in pathogenesis of neointimal hyperplasia. All-trans-retinoic acid (ATRA) is a natural metabolite of vitamin A. Here, we investigated the involvement of AMP-activated protein kinase (AMPK) in the anti-neoi...

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Bibliografski detalji
Izdano u:Front Pharmacol
Glavni autori: Zhang, Jingzhi, Deng, Bo, Jiang, Xiaoli, Cai, Min, Liu, Ningning, Zhang, Shuangwei, Tan, Yongzhen, Huang, Guiqiong, Jin, Wen, Liu, Bin, Liu, Shiming
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2019
Teme:
Pharmacology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6521230/
https://ncbi.nlm.nih.gov/pubmed/31143119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00485
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