All-Trans-Retinoic Acid Suppresses Neointimal Hyperplasia and Inhibits Vascular Smooth Muscle Cell Proliferation and Migration via Activation of AMPK Signaling Pathway

The proliferation and migration of vascular smooth muscle cells (VSMC) is extensively involved in pathogenesis of neointimal hyperplasia. All-trans-retinoic acid (ATRA) is a natural metabolite of vitamin A. Here, we investigated the involvement of AMP-activated protein kinase (AMPK) in the anti-neoi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Pharmacol
Prif Awduron: Zhang, Jingzhi, Deng, Bo, Jiang, Xiaoli, Cai, Min, Liu, Ningning, Zhang, Shuangwei, Tan, Yongzhen, Huang, Guiqiong, Jin, Wen, Liu, Bin, Liu, Shiming
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2019
Pynciau:
Pharmacology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6521230/
https://ncbi.nlm.nih.gov/pubmed/31143119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00485
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