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Germline Missense Variants in BRCA1: New Trends and Challenges for Clinical Annotation
Genetic testing allows for the identification of germline DNA variations, which are associated with a significant increase in the risk of developing breast cancer (BC) and ovarian cancer (OC). Detection of a BRCA1 or BRCA2 pathogenic variant triggers several clinical management actions, which may in...
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| Publicado no: | Cancers (Basel) |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6520942/ https://ncbi.nlm.nih.gov/pubmed/31013702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11040522 |
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