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All the Same? The Secret Life of Prion Strains within Their Target Cells
Prions are infectious β-sheet-rich protein aggregates composed of misfolded prion protein (PrP(Sc)) that do not possess coding nucleic acid. Prions replicate by recruiting and converting normal cellular PrP(C) into infectious isoforms. In the same host species, prion strains target distinct brain re...
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| Publicado no: | Viruses |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6520713/ https://ncbi.nlm.nih.gov/pubmed/30970585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v11040334 |
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