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Monoclonal Antibody Combinations Prevent Serotype A and Serotype B Inhalational Botulism in a Guinea Pig Model
Botulinum neurotoxins (BoNT) are some of the most toxic proteins known, with a human LD(50) of ~1 ng/kg. Equine antitoxin has a half-life in circulation of less than 1 day and is limited to a treatment rather than a prevention indication. The development of monoclonal antibodies (mAbs) may represent...
Guardat en:
| Publicat a: | Toxins (Basel) |
|---|---|
| Autors principals: | , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6520708/ https://ncbi.nlm.nih.gov/pubmed/30959899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins11040208 |
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